As a learner about to begin this educational activity, here’s what you can expect—and why it matters for your practice.

Why Case-Based Learning Matters

Lung cancer remains the leading cause of cancer-related death in the United States, and most cases of non-small cell lung cancer (NSCLC) are diagnosed at an advanced stage. While guidelines recommend comprehensive molecular testing and the integration of immunotherapy, real-world practice often falls short, especially in community and underserved settings. These gaps can lead to missed opportunities for targeted therapy, inconsistent treatment selection, and disparities in patient outcomes.

Co-Chairs

Presenting Faculty

Getting Started

• You’ll begin with an assessment to personalize your learning path. As you progress, the platform adapts to your needs, offering more advanced content or revisiting key concepts as needed. Your participation not only enhances your own skills but also helps shape future educational offerings through feedback and outcomes surveys.
• This activity is designed to fit your learning style and clinical needs, supporting you in delivering the best possible care for patients with advanced NSCLC.

Learning Objectives

This program is designed to help you:

• Identify current guideline recommendations for molecular and biomarker testing in advanced/metastatic NSCLC and recognize common barriers to their implementation.
• Apply multidisciplinary strategies to integrate molecular testing and individualized treatment planning for advanced NSCLC.
• Apply clinical evidence and guideline-based criteria to select appropriate immunotherapy-based regimens for patients with treatment-naive advanced/metastatic NSCLC lacking actionable alterations.
• Implement patient-centered strategies to counsel on immunotherapy goals and manage immune-related adverse events in alignment with best practices.

How the Learning Works

You’ll be using the QDcme Practic-AI platform, which adapts to your needs:

• Personalized Pathways: Start with a brief assessment so the AI can tailor the curriculum to your experience and interests—whether you’re looking for foundational knowledge or advanced strategies.
• Flexible Modules: Short, 15-minute sessions fit your busy schedule and cover essential topics through a mix of video explainers, interactive cases, and evidence-based summaries.
• Real-World Scenarios: You’ll engage with practical, case-based exercises that mirror challenges you see in your own clinic—like explaining biomarker testing to patients or managing complex irAEs.
• On-Demand Support: An AI chatbot is available for quick clinical questions, summarizing medical literature, and reinforcing key concepts as you go.

Support Statement

This activity was supported through an educational grant from Merck Sharp & Dohme LLC.

Target Audience

This activity is intended for community-based medical oncologists, nurse practitioners, physician assistants and other members of the healthcare team who treat and/or manage patients with lung cancer.

Disclosure of Financial Relationships

Postgraduate Institute for Medicine (PIM) requires faculty, planners, and others in control of educational content to disclose all their financial relationships with ineligible companies. All identified financial relationships are thoroughly vetted and mitigated according to PIM policy. PIM is committed to providing its learners with high quality accredited continuing education activities and related materials that promote improvements or quality in healthcare and not a specific proprietary business interest of an ineligible company.

The faculty reported the following relevant financial relationships with ineligible entities related to the educational content of this CE activity:

Laura Alder, MD
Consultant: FoundationOne, OncoHost, Regeneron, Eli Lilly, Genentech, MJH Life Sciences, Boehringer Ingelheim, Amgen, NuvationBio
Research: BerGenBio, ORIC Pharmaceuticals, Iambic Therapeutics

Ticiana Leal, MD
Advisory Board: Amgen, AstraZeneca, Black Diamond, Boehringer-Ingelheim, Bristol-Myers Squibb, Catalyst, Genentech, J&J, Jazz, Merck, Molecular Partners, Naterra, Novocure, Pfizer, Regeneron, Roche, Sanofi, Synthekine, Summit Therapeutics, Takeda, Roche
Consultant: AbbVie, Amgen, AstraZeneca, Boehringer-Ingelheim, Catalyst, Eisai, Gilead, Genentech, J&J, Jazz Pharmaceuticals, Novartis, Novocure, Regeneron, Roche
Research: BerGenBio, ORIC Pharmaceuticals, Iambic Therapeutics

Natasha Leighl, MD
Research: Amgen, AstraZeneca, Boehringer Ingelheim, Bristol Myers Squibb, Eli Lilly, GlaxoSmithKline, Janssen, MSD, Novartis, Pfizer, Takeda, Guardant, Neogenomics

Benjamin Levy, MD
Consultant: AstraZeneca, Merck, Daiichi Sankyo, Janssen

Heather Wakelee, MD
Consultant: IOBiotech, Mirati, OncoC4, BeiGene, GlaxoSmithKline, Bristol Myers Squibb, Genentech/Roche, Merck, AstraZeneca
Research: AstraZeneca, Bayer, BMS, Genentech/Roche, Helsinn, Merck, SeaGen, Xcovery, Gilead

The PIM planners and others have nothing to disclose. The QDcme planners and others have nothing to disclose.

All relevant financial relationships have been mitigated.

Method of Participation and Request for Credit

In order to obtain your CE certificate, please follow the steps below at the conclusion of the activity:

• The Start Activity button will direct you to the Pre-assessment Survey, 15 questions, approximately 10 minutes. Based on your answers you will receive a tailored learning pathway
• At the completion of the Pre-assessment Survey, you may print your score and the correct answer and rationale for each question.
• Press the Save and Exit button, this will direct you to your customized My Learning Page which will contain your learning path of activities
• Choose the first module, designated with a Start Here
• After the pre-test question create an account, it requires only your email and a password, less than 1 minute. The email will be your username
• Complete each module in your learning path
• At the end of each module, you will be directed back your MyLearning Page
• To evaluate and claim credit for any completed activities click on evaluate and claim credit button.
• Complete the evaluation
• After you evaluate the activity, the system will prompt you to choose the certificate type (physician or nurse), the first, last name and degree for your certificate, and the amount of time you are claiming
• Your certificate will be generated with the information provided

If you have questions regarding the certification of this activity, please contact PIM via email at info@QDcme.com

Joint Accreditation Statement

Credit Designation

Physician Continuing Medical Education
The Postgraduate Institute for Medicine designates this enduring material for a maximum of 1.25 AMA PRA Category 1 Credit(s)™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Continuing Nursing Education
The maximum number of hours awarded for this Continuing Nursing Education activity is 1.25 contact hours.
Hardware/Software Requirements (Required for Internet-based ACPE activities only)
Include minimum hardware, software, internet connectivity and connection speed requirements for accessing the internet-based activity.
Policy on Privacy and Confidentiality (Required for Internet-based ACPE activities only)
Please see final activity for the policy on privacy and confidentiality that relates to this internet activity.

Disclosure of Unlabeled Use

This educational activity may contain discussion of published and/or investigational uses of agents that are not indicated by the FDA. The planners of this activity do not recommend the use of any agent outside of the labeled indications. The opinions expressed in the educational activity are those of the faculty and do not necessarily represent the views of the planners. Please refer to the official prescribing information for each product for discussion of approved indications, contraindications, and warnings.

Disclaimer

Participants have an implied responsibility to use the newly acquired information to enhance patient outcomes and their own professional development. The information presented in this activity is not meant to serve as a guideline for patient management. Any procedures, medications, or other courses of diagnosis or treatment discussed or suggested in this activity should not be used by clinicians without evaluation of their patient's conditions and possible contraindications and/or dangers in use, review of any applicable manufacturer's product information, and comparison with recommendations of other authorities.